“This event is an Accredited Group Learning Activity as defined by the CSCC/CACB Professional Development Program.”
« Cette activité est une activité de formation collective agréée selon la définition établie par le Programme de perfectionnement professionnel de la SCCC et l’ACBC. »

  Thursday June 25, 2020

1200-1400 EDT

Indigenous Health: Time for Action

 Co-chairs: Cheryl Greenberg, Research Scientist, Children’s Hospital Research Institute of Manitoba, Winnipeg, MB
Laurel Thorlacius, Clinical Biochemistry, Shared Health, Winnipeg, MB 
1200 Welcome and Opening Blessing
Leslie Spillett, Knowledge Keeper, Ongomiizwin Indigenous Institute of Health and Healing, Rady Centre of Health Sciences, University of Manitoba
1210 The Health Status of and Access to Healthcare by Registered First Nations Peoples in Manitoba
Speakers:  Alan Katz, Professor, University of Manitoba, Winnipeg MB
Kathi Avery Kinew, Instructor in Native Studies, University of Manitoba
Objectives:  At the end of the session participants will be able to:
1. Describe the differences in health status of First Nations in Manitoba
2. Describe some of the relevant underlying determinants of
3. Discuss the consequences for practice 
Overview: The presentation presents results of an comparison between the health status and health system use between Registered First Nations People and all other Manitobans. The session will be of value to: Geneticists, Trainees, Medical Students, Residents to provide context to the care they provide. 
1250  Stepping back - Tackling health disparities through a moral and historical lens 
Speakers:  Jon McGavok, Assicuate Professor, Children’s Hospital Research Institute of Manitoba, Winnipeg MB
Taylor Morriseau, PhD Candidate, Children’s Hospital Research Institute of Manitoba, Winnipeg, MB 
Objectives:  At the end of this session, participants will be able to:
1. Explain the concept that sovereignty and self-determination are determinants of health for Indigenous People
2. Explain the importance of “Being Woke” when tackling questions
3. Provide examples and resources for Settlers to tackle research questions in a moral way
4. Provide an example of tackling a genetic-based research question related to diabetes disparities in Indigenous community in the right way 
Overview:  We will describe the critical importance of understanding the historical realities and sovereign relationships between settlers and Indigenous People in Canada when tackling research questions about health disparities, particularly disparities in rates of diabetes and it's complications. We will provide examples of best and worst practices from past genetic research related to disparities in diabetes rates among Indigenous people worldwide. Finally, we will describe our own journeys in researching diabetes within and then beyond Western colonial institutions. Delegates will leave the session with a better understanding of the moral compass and larger worldview necessary to tackle disparities research, including genetic research, in a more meaningful way. 
1335  When rare becomes common: Understanding the genetics of sudden death and implications for other heart disease with the help of a Founder population
Speaker:  Laura Arbour, Professor, University of British Columbia, Victoria BC 
Objectives:  At the end of this session, participants will be able to:
1. Identify the known genetic contributors to sudden cardiac death in Northern BC, and the management strategies in place for prevention.
2. Describe the association of the ANK2 p.S646F variants with features of common heart disease and how scientific evidence is being collected to understand the basis.
3. Describe how participatory research within a Founder population can enhance the understanding of genotype/phenotype correlations in conditions with variable expressivity.
Overview: Although relatively rare (1/2000) Long QT syndrome, a genetic predisposition to cardiac arrhythmia and sudden death is at least 15 times more common in the Gitxsan First Nation, a remote community in Northern British Columbia (BC) whose ancestors have resided in the region for thousands of years. The frequency in this community is consistent with one or more ‘founder effects’, whereby rare autosomal dominant conditions not affecting fecundity may become common as rare variants are passed from generation to generation. We have previously identified a pathogenic variant (KCNQ1 p.V205M) which could be traced back at least seven generations explaining LQTS in the majority of cases in that region. Until recently we were unable to identify a potentially causal variant in a second group of kindreds with LQTS but lacking the KCNQ1 variant. A variant in ANK2 (p.S646F) has now been identified in those kindreds and is associated with a LQTS phenotype with increasing age, sudden death in the young, as well as more common heart disease such as congenital heart malformations (1/15 carriers), and cardiomyopathy. This presentation will describe the participatory research leading to the discoveries, clinical and laboratory studies carried out to date and underway to ascertain the cellular mechanisms leading to pathology. These studies may have implications for common heart disease in general.
1410 The Intersection of Medicine and Society, Reviewing Jordan’s Principle 
Speaker: Brian Postl, Dean, Max Rady College of Medicine, Dean, Rady Faculty of Health Sciences, Vice-Provost (Health Sciences), University of Maniatoba, Winnipeg MB
Objectives: At the end of the session participants will be able to:
1. Understand the principles outlined in the UN Declaration of the Rights of Indigenous people
2. Understand the impact of the Residential School system on the health of Indigenous children and their families
3. Understand who Jordan River Anderson was and how his story ultimately led to the passing and implementation of the federal Private Member's bill known as Jordan's Principle. The Bill addresses the jurisdictional disputes between government parties which disrupt access to health services for Indigenous children.
Overview: Dr. Postl will provide a historical overview of Canada, the marginalization of Indigenous peoples and its impact on Indigenous health status. In telling the story of Jordan River Anderson and Jordan's Principle, the take home message is one of the value of Indigenous children and the Universal Rights of Indigenous people.